2ack



ACETYLCHOLINESTERASE COMPLEXED WITH EDROPHONIUM, MONOCHROMATIC DATA

See also AChE inhibitors and substrates (Part II).



Edrophonium (EDR) is stacked between the aromatic rings of W84 and F330, near the TcAChE catalytic triad which consists of 'S200' , 'E327' , and 'H440'.

About this Structure
2ACK is a Single protein structure of sequence from Torpedo californica. This structure supersedes the now removed PDB entry 1ack. Full crystallographic information is available from OCA.

Additional Resources
For additional information, see: Alzheimer's Disease

Reference
Static Laue diffraction studies on acetylcholinesterase., Ravelli RB, Raves ML, Ren Z, Bourgeois D, Roth M, Kroon J, Silman I, Sussman JL, Acta Crystallogr D Biol Crystallogr. 1998 Nov 1;54(Pt 6 Pt 2):1359-66. PMID:10089512

Page seeded by OCA on Sat May 3 18:52:49 2008